Kissing disease is an infection caused by the Epstein-Barr virus (EBV); it gets its name because it spreads through saliva. In young children it usually runs a mild or asymptomatic course, while the more dramatic picture is seen in adolescents.

Symptoms

  • Fever that may last 1–2 weeks
  • Severe sore throat; widespread white-grey exudate on the tonsils (easily confused with strep)
  • Prominent swollen lymph nodes in the neck
  • Intense weakness and fatigue (which can last for weeks)
  • Swelling of the eyelids, sometimes a faint rash
  • Enlargement of the spleen and liver

Why Is It Important?

In children with EBV who are mistakenly treated for strep with amoxicillin-group antibiotics, a widespread rash can develop — this is yet another reason to avoid unnecessary antibiotics. The diagnosis is made through examination, a complete blood count (atypical lymphocytes), and EBV antibody tests.

Treatment and Things to Watch For

There is no specific treatment; rest, plenty of fluids, and control of pain and fever are essential. Because the spleen may be enlarged, throughout the illness and until your doctor gives approval (usually 3–4 weeks) contact sports and any blows to the body should be avoided — this rule is important because of the risk of splenic injury.

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Related articles: Tonsillitis · Prolonged fever

This article is for general information purposes only and does not replace diagnosis or treatment. For any concerns about your child's health, be sure to consult a pediatric specialist.

Uzm. Dr. Hasan Keleş — Pediatrician (Specialist in Child Health and Diseases), Gaziantep